![]() The Toolkit currently includes 35 in-house and external tools for sequence similarity searching calculation of multiple sequence alignments prediction of secondary structure and sequence features and sequence classification. The Toolkit has been in continuous operation ever since, and we replaced the first version with an entirely new one built using more scalable and robust web technologies in 2017 (Alva, Nam, Soding, & Lupas, 2016 Zimmermann et al., 2018). ![]() Driven by our work at the interface of computational and experimental biology, we launched the MPI Bioinformatics Toolkit in 2005 to provide researchers in the life sciences with easy, web-based access to the best-performing bioinformatics tools and databases (Biegert, Mayer, Remmert, Soding, & Lupas, 2006). Over the years, many high-quality sequence search methods protein sequence and domain databases and integrative Web resources have been developed to help researchers make meaningful inferences based on homology. Sequence searches are a common first step in this process, as sequence similarity is widely accepted as the best marker for substantiating homologous relationships. The structure, function, and evolution of new or uncharacterized proteins are routinely inferred based on their homology to proteins with experimentally characterized properties. Support Protocol: Building a custom multiple sequence alignment using PSI-BLAST and forwarding it as input to HHpredīasic Protocol 2: Calculation of homology models using HHpred and MODELLERīasic Protocol 3: Cluster analysis using CLANS © 2020 The Authors.īasic Protocol 1: Sequence similarity searching using HHpredĪlternate Protocol: Pairwise sequence comparison using HHpred In this article, we provide detailed information on utilizing the three most widely accessed tools within the Toolkit: HHpred for the detection of homologs, HHpred in conjunction with MODELLER for structure prediction and homology modeling, and CLANS for the visualization of relationships in large sequence datasets. Due to this breadth of functionality, the tight interconnection of its constituent tools, and its ease of use, the Toolkit has become an important resource for biomedical research and for teaching protein sequence analysis to students in the life sciences. The Toolkit currently includes 35 external and in-house tools, covering functionalities such as sequence similarity searching, prediction of sequence features, and sequence classification. The MPI Bioinformatics Toolkit ( ) provides interactive access to a wide range of the best-performing bioinformatics tools and databases, including the state-of-the-art protein sequence comparison methods HHblits and HHpred.
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![]() Shepherd writes: "Maps were love letters written to times and places their makers had explored. Tolkien's Middle-earth or Terry Pratchett's Discworld. Cartography buffs will delight in the profusion of iconic maps in these pages - from historical marvels like the mediaeval Venetian Fra Mauro, to maps of fantasy realms such as J. What makes the book a worthwhile read is how Shepherd captures the magic of maps. Romances on which the plot turns do not compel, and a major reveal can be spotted a mile away. Nell is surrounded by a plethora of characters who are not fleshed out enough to be distinctive. The Cartographers has a clever premise, though it is a better concept than it is a novel. People seem to walk through walls, and the connection between a map and reality is a secret some would kill for. Garcia, Dr.Nell's investigation takes her into a dangerous world where places appear one moment and vanish the next. ::omakase::300:250 Author Sumthinblue Posted on 2 April, 2010 Categories Book Events, Book Reviews Tags ancient maps, Carlos Quirino, cartography, Dr. Philippine Cartography by Carlos Quirino, hardcover, 5/5 stars VFI specializes in knowledge – the preservation and distribution of as much of it as possible, hence its various print and website projects. Vibal Foundation is the non-profit arm of Vibal Publishing House Inc., a company best known for textbooks for students in the elementary and high school levels. “We can strengthen our self-esteem and love for country by tracing our roots in history and geography.” Maps give us a sense of memory and identity,” Dr. “Maps help us find our place in the world, telling us not only where we are and where we want to go, but also who we are. ![]() The book is hardcover, with glossy pages, a gilded edge, and special pull-out sections - everything that will make your mouth water, whether you’re a cartophile, a bibliophile, or anywhere in between. It also showcases the most comprehensive bibliography of Philippine maps, and a fresh and authoritative introduction by Dr. These are only three of over a hundred maps showcased in Philippine Cartography, from ancient Chinese scrolls to intricate atlases from the finest collections, all in quality reproductions. What’s amazing about all these maps is how they offer a view from above, centuries before air travel was invented! Ancient maps were created by pure triangulation and imagination (sometimes even depicting magical creatures!), often inaccurate, but no less breathtaking. It is said to be the mother of all Philippine maps, in which the current iconography of the Philippine map is rooted. Pedro Murillo Velarde and printed by Filipino woodblock artist Nicolas de la Cruz Bagay. The Murillo Velarde map is the first detailed map of the Philippines, drawn in 1744 by the Spanish Jesuit cartographer Fr. Pedro Murillo Velarde Carta hydrographica y chorographica de las islas Filipinas (1734). It’s interesting to note the different orientation of this map - it’s sideways!įr. The Insulae Philippinae is the first separate map of the Philippines. Pieter van den Keere Insulae Philippinae (1605). ![]() Garcia introduced us to the Ramusio-Gastaldi map, the Philippines’ “birth certificate.” This map records the first appearance of the word “Filipina” on a western document! Juana Madriaga Garcia-Natividad Galang Fajardo Map Collection.ĭr. Ramusio-Gastaldi Terza ostro tavola (1563). “They are documents of history, a visual representation of experience of a dominating point of view.” “Maps are mark of power, vessels of knowledge, and icons of beauty,” states Dr. ![]() Leovino Garcia, editor of Philippine Cartography, was there for the tour (incidentally, he was the Dean of the School of Humanities back when I was in college at the Ateneo de Manila University) to talk about the book, and he gave us some great insights about maps. First published in 1959, the book traces the evolution of the Philippine map, from a speck in the Pacific Ocean to its current iconography.ĭr. A couple of weeks ago I had the pleasure of joining a media tour at the exhibit “Pen, Paper and Bookmaking: The Life of Carlos Quirino” at the Yuchengco Museum.Ĭarlos Quirino, National Artist for Historical Literature, is a writer, scholar, sportsman, and bibliophile who made invaluable contributions to the study of Philippine history.Ģ010 marks Quirino’s birth centennial, and in celebration of this auspicious event, three erstwhile out of print Carlos Quirino books are lined up for release by the Vibal Foundation: Philippine Cartography, Old Manila, and Filipinos at War.įirst out is the third edition Philippine Cartography, a landmark history of Philippine maps and their cartographers, considered as Quirino’s magnum opus. ![]() They are in no way an absolute protection against deletion, they just provide guidance to Unison about how to decide on the default action. Remember, these options can be overridden in interactive mode by the user. In batch mode, changes with default actions will accepted, changes without default action (due to conflicts) will be skipped. When you are satisfied with the default actions, you can run unison in batch mode (option -batch) using the textual UI. Working with the graphical UI is more convenient as you see all pending changes including the default actions Unison suggests. ![]() Until you have set up Unison to run in batch mode, I recommend to run Unison in interactive mode using the graphical UI. So in total you want to run Unison with these two options to satisfy your requirements: unison /src/dir /dest/dir -force /src/dir -nodeletion /dest/dir The commandline to preserve files on /dest/dir after they have been deleted from /src/dir would be unison /src/dir /dest/dir -nodeletion /dest/dir Use the option -nodeletion xxx to prevent Unison from recommending any deletion on the folder xxx as default action. The commandline to mirror, e.g., folder /src/dir to /dest/dir would be unison /src/dir /dest/dir -force /src/dir Unison will resolve all changes in favor of this folder. The force option takes the folder that is to be favored as argument. Unison has a clear and precise specification.I understand that you are having these two requirements on UnisonĪccording to the Unison manual, the -force xxx option "effectively changes Unison from a synchronizer into a mirroring utility".It is careful to leave the replicas and its own private structures in a sensible state at all times, even in case of abnormal termination or communication failures. Transfers of small updates to large files are optimized using a compression protocol similar to rsync. It is careful with network bandwidth, and runs well over slow links such as PPP connections. Unison works between any pair of machines connected to the internet, communicating over either a direct socket link or tunneling over an encrypted ssh connection.Unlike a distributed filesystem, Unison is a user-level program: there is no need to modify the kernel or to have superuser privileges on either host.Conflicting updates are detected and displayed. Updates that do not conflict are propagated automatically. Unlike simple mirroring or backup utilities, Unison can deal with updates to both replicas of a distributed directory structure.Moreover, Unison works across platforms, allowing you to synchronize a Windows laptop with a Unix server, for example. ![]() Unison runs on both Windows and many flavors of Unix (Solaris, Linux, OS X, etc.) systems.Here are some key features of "Unison File Synchronizer": ![]() Unison shares a number of features with tools such as configuration management packages(CVS, BitKeeper, PRCS, Subversion, etc.), distributed filesystems (Coda, etc.), uni-directional mirroring utilities (rsync, etc.), and other synchronizers (Intellisync, Reconcile, etc). It allows two replicas of a collection of files and directories to be stored on different hosts (or different disks on the same host), modified separately, and then brought up to date by propagating the changes in each replica to the other. Unison is a file-synchronization tool for Unix and Windows. Unison File Synchronizer - A file-synchronization tool that allows two replicas of files to be stored on different hosts Version: 2.27.72 There are also options that help to make Tux paint suitable for younger or disabled children such as display text using uppercase letters or ignoring the distinction between buttons on the mouse. Parental and teacher controls allows them to disable features and alter the behavior to better suit their children or student needs, typical options such as enabling or disabling sound effects and full screen mode are available. Large collection of artwork and photographic imagery are also available In Tux paint user does not require to provide file name or browse for where to place it, with the help to thumbnails(reduced size version of picture or videos) user can select file he/ she want.Īdvanced drawing tools include different types of filters and special effects which can be applied to drawing such as blurring, fading and making the picture look as though it was drawn in chalk and pavement all these are available through the magic tools in Tux paint, Magic tools are built as plug-ins that are loaded at runtime and use a CAPI specifically for creating such tools. ![]() Tux paint is a typical graphics editing software which is design for young as 3 year of age children, feature that help user to understand how software works are the user interface( where human and computer interact), icons, audible feedback and textual hints and bright colors, sound effects and cartoon mascot helps in engaging children.īasic drawing tools include a paintbrush, an eraser and tools to draw lines, polygonal shapes and test, undo and redo option also available in order to remove accidental or unwanted changes while editing a picture. Tux paint is introduced by Bill Kendrick in 2002, Tux is free and open source software specially introduce for young children, it is a raster graphics editor(a program that allows users to create and edit image interactively on the computer screen and save them in JPEG, PNG, GIF.) Tux use in operating system like Linux, Microsoft Windows, Apple Mac OS X, BeOS and other platforms as well. Kids are presented with a blank canvas and a variety of drawing tools to help them be creative. It combines an easy-to-use interface, fun sound effects, and an encouraging cartoon mascot who guides children as they use the program. Tux Paint is used in schools around the world as a computer literacy drawing activity. Tux paint is one of the most famous software used for drawing purposes But there are many drawing software’s apart from them. ![]() Traditionally we use MS paint as drawing tool. A simple graphics educational painting programs for young children. Version: 0.9.28-windows-sdl2.0-i686 (2022.06.Tux Paint is a free and Open Source Drawing Software for Children. Learn how to tell which you have with this Microsoft FAQ article. for Windows is available for both newer 64-bit (' x86_64') and older 32-bit (' i686') CPU architectures. June 4, 2022-JTux Paint 0.9.28 has been released and is currently available for download for Microsoft Windows, Apple macOS, Android, Red Hat Linux, Slackware Linux, Haiku, various Linux distributions (via Flatpak) and as source code. ![]() The number of concurrent HTTP connections for Chat was configured to the maximum.Windows Access Control List (ACL) IntegrationĪdd-on Packages (learn more about the complete add-on package list) Maximum Concurrent CIFS/AFP/FTP Connections exFAT Access is purchased separately in Package Center.īrightness adjustable front LED indicators.HFS+ is read only, max 2TB volume size. ![]() 2.5″ SATA III / SATA II SSD (with optional 2.5″ Disk Holder)ġ0 TB (10 TB HDD x 1) (Capacity may vary by RAID types).2.5″ SATA III / SATA II HDD (with optional 2.5″ Disk Holder).Let’s take a look at the specifications and feature then we will take a look inside the DS116… Specifications Hardware SpecificationsĬompatible Drive Type* (See all supported drives) Included is an RJ45 Ethernet cable, an AC/DC 36w power adapter and enough screws to mount a 3.5” HDD inside the unit there are 2 screws to spare making 6 included in total in case you are like me and clumsily lose screws! Inside the box aside from the NAS itself, is a couple of useful and necessary accessories. The exterior panels have a softish plastic coating which is a bit of a fingerprint magnet, so if that kind of finish puts you off…stop being pedantic! It’s not that bad and if you think about it rationally, you usually only really touch the exterior when moving, or installing/removing the singular 3.5” HDD from the unit. Also featured on the back panel is a conveniently placed Kensington Lock, 2 x USB 3.0 ports for the connection if external hard drives, a dc input for the 36w power adapter and a single RJ45 Ethernet port for connection to your network. Featured towards the bottom right is a power button this also has a built-in LED showing whether the unit is powered on or off.Ĭooling the DS116 and keeping it from overheating is a small 60圆0x15mm fan from Y.S TECH who actually make one of my favourite 60mm fans, the 25mm thick FD1260257B the hot air on this model is vented out towards the rear. On the front panel, there are LED notification slits for status, LAN and Disk essentially allowing you to see if each different part of the operational cycle is working as intended. Not only does this power and keep the NAS unit ticking over, but it also enables Synology DSM (Diskstation Manager) the headroom it needs to work. This is because this 1 bay NAS is loaded with a Marvel Armada 385 88F6820 dual-core 1.8GHz processor which is complimented by 1GB of DDR3 memory. ![]() This not only looks very professional and stylish, but it also doubles up as air ventilation. The unit features an all-black design and has a medium sized Synology logo etched into both side panels of the unit. The Synology DS116 isn’t just a NAS as we know it, but it’s touted as a ‘private cloud’ which enables users to not only store their data, but it also allows for syncing across multiple platforms and cloud services such as Dropbox, OneDrive, and Google Drive very handy for adopters of those particular services. The Synology DS116 Diskstation 1 bay NAS covers both of those bases and then some… Others want to be able to share their documents across a network securely, but without the hassle of using a paid subscription service such as Dropbox and numerous other cloud services. There are numerous methods of storing your precious and important files these days, but most people I know personally prefer having ‘hard’ copies in case of tragedy. # are repository servers and will give you the ability to manage multiple # Chocolatey Software recommends Nexus, Artifactory Pro, or ProGet as they # generally really quick to set up and there are quite a few options. # You'll need an internal/private cloud repository you can use. Internal/Private Cloud Repository Set Up # # Here are the requirements necessary to ensure this is successful. Your use of the packages on this site means you understand they are not supported or guaranteed in any way. With any edition of Chocolatey (including the free open source edition), you can host your own packages and cache or internalize existing community packages. Packages offered here are subject to distribution rights, which means they may need to reach out further to the internet to the official locations to download files at runtime.įortunately, distribution rights do not apply for internal use. If you are an organization using Chocolatey, we want your experience to be fully reliable.ĭue to the nature of this publicly offered repository, reliability cannot be guaranteed. Human moderators who give final review and sign off.Security, consistency, and quality checking.ModerationĮvery version of each package undergoes a rigorous moderation process before it goes live that typically includes: ![]() ![]() ![]() Welcome to the Chocolatey Community Package Repository! The packages found in this section of the site are provided, maintained, and moderated by the community. ![]() (10) But, we found that the Roux-Y type bypass operation using the pedicled jejumun was a safe and uninvasive procedure for a patient with high risk.(9) Other recommendations for immediate action included a review of the Nursing and Midwifery Council and the General Medical Council for doctors, with possible changes to their structures the possible transfer of powers to launch criminal prosecutions for care scandals from the Health and Safety Executive to the Care Quality Council and a new inspection regime, which would focus more closely on how clean, safe and caring hospitals were.(8) The exception to this rule is a cyst which can be safely aspirated under controlled conditions.(7) Infusion of vincristine may be safely incorporated into multiagent chemotherapy programs of the CHOP type for non-Hodgkin's lymphoma.(6) Comprehensive regulations are being developed to limit human exposure to contamination in drinking water by the United States Environmental Protection Agency (EPA) under the authority of the Safe Drinking Water Act (SDWA).(5) Our experience indicates that lateral rhinotomy is a safe, repeatable and cosmetically sound procedure that provides and excellent surgical approach to the nasal cavity and sinuses.(4) This is an easy, safe, and rapid alternative for the emergent treatment of superior vena caval syndrome. ![]()
Login and consistency of interface and configuring Apache is like Windoze - popular, but hard to figure out why as it is so bloated and awkward. We are about move all of our servers from Apache to Abyss. Things that take Apache down are barely a blip for Abyss. As an added bonus you can often get features added to the products based on your own suggestions!īeen using Abyss for years now in a commercial web hosting environment and it has been PERFECTLY stable. ProVue made the second piece of software for the Mac and it is still around.īuy small and buy quality as it will save time and money (even over the "free" products). You often get MUCH better products, better support, and surprisingly longer life products. I now recommend dealing mostly with small companies that make great products such as ProVue (makes the great database Panorama), HindSight (photo business software), Aprelium, etc. They actually read your questions and give reasonable and quick answers even for complex issues.Īfter wasting years of my life with open source products such as Apache where you search in forum after forum for months only to get numerous stupid and wrong answers especially when dealing with utterly absurd mod_rewrite and, after dealing with the big companies such as Adobe, Epson, Apple, Micro$oft, Comcast, etc where the techs often times know little and deny obvious bugs, dealing with Aprelium is a breath of fresh air. The tech support for Abyss is great!! With the very reasonably priced Pro version, you get priority support. I regretfully have to take off a star for not being 64bit on Mac yet. Works great as a PHP testing server, IMHO, as well. That said, never had a hacking issue with it either, but then again I practice lots of safeguards I won't get into here.įantastic server. If you don't have any clue about how to run them, you probably shouldn't be opening up your computer/server/whatever to the world anyway. The interface isn't perfect and there's a lot of areas that are not going to be self-explainatory, but hey, it's a web server. I try out MAMP every now and then, shrug. ![]() I've never had it crash or interfere with anything else on any computer.Īs a testing server, I've found it better than MAMP and it doesn't download huge amount of crap like MAMP does and they aren't pushy (like the MAMP people are) about getting the paid version. I just realized I've been using this a really long time and I don't remember if I've ever reviewed it here. Hmmm, it would also be nice to see a very minimalistic CMS. My major wish now is for Aprelium to create a FTP server. ![]() ![]() ![]() Since it is easy to change the XML config file, I just wrote my own simple admin program in the database Panorama and do bulk changes to hundreds of web sites in just a few seconds. While the web browser admin interface works well and it easy to figure out (with the ever-present contextual help button), I would like to see some changes in just the look and feel and the ability to do bulk changes. htaccess files right there in the admin console rather than in hiddn files scattered all over the machine! It's also nice to do most of the features of. You forget it is there as you only need to access it for adding new virtual hosts. All the major features are now there.Ībyss is fast, hyper-stable, very low memory and CPU usage, and feature rich and their email support is nearly impeccable. I can only recall one crash (it actually may have been the fault of the OS) and only one difficult to pin down bug (involved PHP).Īnd now, with the latest version they have added the one essential feature that I have needed - log rotation. I've now used Abyss for around a decade for commercial web hosting on multiple servers and it has probably been the most stable and near bug free piece of software that I have ever used. The Associated Press contributed to this report. LeBron James was previously announced as the cover star for the "NBA 2K19" 20th anniversary edition, which will be available on Sept. To view all NBA 2K19 screenshots, check out the constantly updated NBA 2K19 Screenshots Tracker. ![]() I am honored to be the first international player featured on the cover of Pre-orders are now available #NBA2K19 /gWZBcCMHVF- Giannis Antetokounmpo July 2, 2018 Check out this new NBA 2K19 screenshot and player rating of NBA 2K19 cover athlete Giannis Antetokounmpo. He also tweeted that he was "honored" to be the first international player to be on the video game's cover. The NBA2K19 cover athlete, is Giannis Antetokounmpo and Double Clutch has been in Athens to celebrate the announcement of the first ever International cover athlete. The two-time NBA All-Star known as the "Greek Freak" is the first international player to be featured on the cover.Īntetokounmpo said he has "worked hard to earn recognition in the NBA and being on the cover of NBA 2K19 is a dream come true." Milwaukee Bucks forward Giannis Antetokounmpo is the cover athlete for the "NBA 2K19" standard-edition video game. Series 1 features reigining NBA MVP James Harden, NBA 2K19 cover athlete Giannis Antetokounmpo, as well as dominant stars: Russell Westbrook, Kevin Durant. Giannis Antetokounmpo has been named the NBA 2K19 standard edition cover star, 2K today confirmed. Current star Giannis Antetokounmpo of the Milwaukee Bucks is the cover athlete for the standard edition version of the game, while current star LeBron James of the Los Angeles Lakers is the cover athlete for the 20th Anniversary Edition, which includes various physical and digital extras. ![]() If the holiday is not listed below, Wells Fargo Bank will not be closed for that holiday. While most banks close on federal holidays, and this is the case with Columbus Day as well, there are more banks open on this federal. Many schools will be closed on Columbus Day. Do not assume if another bank is closed that every bank is closed. Some banks are open on Columbus Day, but most are closed. Heres what businesses will be open or closed on Monday: Banks : Most banks, including Federal Reserve Banks, Bank of America. If Monday is your normal recycling pickup day, put your recycling out after 4 p.m. Banks: Most banks, including Federal Reserve Banks, Bank of America and Wells Fargo, will be closed. Some cities have replaced Columbus Day with Indigenous Peoples Day. ![]() Residents whose usual garbage or organics pickup day is Monday should put their trash out after 4 p.m. Garbage, recycling and organics collection will not occur on Monday, Oct. ![]() Call your local branch to check its hours.Īlternate side parking rules will be suspended. Day Presidents Day (also referred to as Washingtons Birthday) Memorial Day. If you bank with one of these financial institutions, you’ll most likely need to wait until Oct. On which holidays is the bank closed New Years Day Martin Luther King Jr. The annual Columbus Day Parade has been canceled this year due to the coronavirus.Ĭity, state and federal government offices, including courts and post offices, are closed. Banks Closed on Columbus Day Here’s a look at banks that close in observance of the holiday, so you can plan accordingly. Holiday Closings Columbus Day, Monday, October 10, 2022, Closed Veterans Day, Friday, November 11, 2022, Closed Thanksgiving, Thursday, November 24, 2022. Here’s a look at what’s open and closed around New York City. No matter how you spend the holiday, various closures may impact your daily routine. On average, 88 percent of the students who identified as Democrats supported the name change, and only 22 percent of Republicans polled were in favor of swapping the names. |
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